Innovator

“If at first the idea is not absurd, then there is no hope for it.”
– Albert Einstein

Implants & Devices


Scaphoid

Role: Lead Consulting Surgeon
Equipment: TwinFix Screw – Stryker Corporation

A headless cannulated compression screw that allows independent control of both leading and trailing threads in order to precisely compress scaphoid fracture fragments. The screw is inserted across the fracture fragments as one unit then the trailing head is disengaged, and the by continuing to advance the leading threads, fracture compression and stability is obtained.


The screw is inserted as a single unit.

 

The trailing portion of the screw (blue) is disengaged from the driver but the leading threads (gold) continue to advance as the driver is turned thus compressing the fragments.

 

A clinical example of use of the TwinFix screw to treat a scaphoid waist fracture

 
Distal Radius

Role: Consulting Surgeon
Equipment: Volar Variable Angle Locking Plate – Stryker Corporation

 

Role: Consulting Surgeon
Equipment: Fragment Specific Distal Radius and Ulna Fixation – Stryker Corporation


A clinical example showing the use of both the volar plate and fragment specific radial column fixation for an exceedingly complex distal radius fracture.

 

Role: Developing Surgeon
Equipment: CoverLoc Volar Plate – Deo Volente Orthopedics → Tornier Corp. → Wright Medical

CAD 3D modeling focusing on plate size and contour as well as screw position for maximum capture of the most common fracture patterns. The design emphasizes low profile positioning (even distally at the “water-shed line”) which allows capture of distal fragments common in fragility fractures, and fixed angle non-locking screws which simultaneously allow for stable fixation and lag screw function.

 

A clinical example of a displaced, angulated, multi-fragmented, and comminuted intra-articular (arrow) distal radius fracture.

 

Anatomic reduction of the fracture and its component parts utilizing the fixed angle stainless steel CoverLoc plate.

 

Role: Developing Surgeon
Equipment: Dorsal IM (Intra-medullary) Plate – Deo Volente Orthopedics → Tornier Corp.


Design sequence and evolution

 


Cadaver testing during the design phase

 

Final CAD model with fixed angle screws that can also perform a “lag” function. The combination of the dorsal plate and intramedullary stem emphasized buttress fixation and stability.

 


A clinical example of a displaced and angulated primarily extra-articular distal radius fracture with significant dorsal comminution (arrow).

 

The fracture is reduced using the concept of buttress fixation and fragment stability through combined lag screw and fixed angle techniques, approaches especially valuable in highly osteoporotic bone. The limited exposure for this procedure allowed a rapid return to function.

 

Role: Lead Consulting Surgeon
Equipment: Intrafocal (Intra-medullary) Pin Plate – Deo Volente Orthopedics → Tornier Corp.

This design focused on limited exposure and buttress fixation with intrafocal placement.

 

This elderly patient sustained a very distal intra-articular distal radius fracture with displacement, angulation and comminution highly characteristic of a fragility fracture.

 

Limited dorsal and radial incisions were made, the stem was placed through the fracture site and the plate used to buttress the reduced fracture in place. Screws were used for added stability. The limited nature of the procedure meant very little operative time for this patient with multiple severe medical problems.

 

The patient was lost to follow-up for 3 month all the awhile without any external support (cast/splint). These Xrays revealed anatomic reduction and healed fractures. Her motion was virtually full.

 

Science/Discovery


Scientific Appointments

Innovation Advisory Council
Texas Medical Center Innovation Institute (TMCx)

Bone Core Member / Program Advisory Committee
The Rolanette and Berdon Lawrence Bone Disease Program of Texas
Texas Medical Center

Senior Scientist
UAB Center for Metabolic Bone Disease

Senior Scientist / Internal Advisory Committee
UAB Arthritis and Musculoskeletal Center

Senior Scientist / Internal Advisory Committee
UAB Center for Education and Research of Therapeutics of Musculoskeletal Disorders

Senior Scientist / Steering Committee Member
UAB Biomatrix Engineering and Regenerative Medicine Center

Research Support

Osteoinduction
Healing of a segmental defect in the rat femur using an extract from a cultured human osteosarcoma cell line (SAOS)
American Fracture Association
Principal Investigator

Kienbock’s Disease
The role of protein C, protein S, anti-thrombin III, and tissue plasminogen activator in Kienbock’s disease
The Cleveland Clinic Foundation – Research Programs Com. / Dept. of Orthopaedics
Principle Investigator

Tissue Engineering
Porcine small intestine submucosa (SAS) as a flexor tendon graft in the dog model
Depuy Corporation
Co-investigator (PI’s – Derwin K and Iannotti J)

Intra-osseous Compression Screw Fixation
Biomechanical characteristics of intra-osseous, compression screws for small bone fixation
Stryker / Leibinger, Zimmer, Normed Corporations
Principle Investigator

Enhancement of a Biomechanics Core with Low Force Testing
Health Services Foundation – General Endowment Grant
Co-investigator / Contributor (PI – Eberhardt A)

Biomechanical and Finite Element Analysis of a Stainless Steel Lag-Locking Distal Radius Plate v. a Locking Titanium Plate System for Fixation of an Intra-Articular Distal Radius Fracture
Tornier Corporation
Principle Investigator

Development of a Patient Reported Outcomes Program
Hackett Family Foundation
Principle Investigator

Creating Surgical Capabilities for Exploration Space Flight
NASA – Translational Research Institute for Space Health
Co-investigator (PI – Pantalos G)

Epidemiological, image, and video analysis of metacarpal fractures in National Football League players with special emphasis on mechanism of injury, fracture and player characteristics, and outcomes of care.
National Football League
Principle Investigator

The frequency, characterization, and health impact of “wrist sprains” on National Football League players
National Football League
Principle Investigator

Consultancy and advisory positions greater than 3

Ongoing Research

The frequency, characterization, and health impact of “wrist sprains” on National Football League players

Musculoskeletal Biology and Medicine Resource – Based Center (P30 NIAMS proposal 06/2018)
Biorepository – Associate Director

Epidemiological, image, and video analysis of metacarpal fractures in National Football League Players with special emphasis on mechanism of injury, fracture and player characteristics, and outcome of care.

Gene Expression and Biomechanical Analysis of Human Tendons and Ligaments in Injured and Uninjured States

Patient Reported Outcomes Following Care of Musculoskeletal Disorders

Rates and Trends of Open v. Endoscopic Carpal Tunnel Release at the Veteran’s Affairs Medical Centers: Implications for Cost Savings and Outcome.

Genetic Basis of Peyronie’s and Dupuytren’s Diseases

Characterization of the Phenotype of Focal Dermal Hypoplasia (Goltz Syndrome) to Improve the Medical Care and Creation of a Biobank for Research

3D Scanning and printing for Wrist Injury Therapeutics (3D-Wrist): Implications for Space Flight

Creation of a Skeletal Biology Biorepository (Baylor St. Luke’s Medical Center, Ben Taub General Hospital and Michael DeBakey Veteran’s Affairs Medical Center)

Creation of Surgical Capabilities for Exploration Space Flight – Multicenter protocol (Local PI)

Innovation and Commercialization

Distal radius locking plate and screw construct
Design team
Stryker Corp

Two-part headless, cannulated, compression screw
Design team – lead
Stryker Corp

Fixed angle, non-locking distal radius plate and screw construct
Surgeon designer
Deo Volente Orthopedics

Pin plate fracture fixation device
Surgeon designer
Deo Volente Orthopedics

Intramedullary wrist fusion plate
Surgeon designer
Deo Volente Orthopedics